"Mushi": the most basic forms of life in the world. They exist without any goals or purposes aside from simply "being." They are beyond the shackles of the words "good" and "evil." Mushi can exist in countless forms and are capable of mimicking things from the natural world such as plants, diseases, and even phenomena like rainbows. This is, however, just a vague definition of these entities that inhabit the vibrant world of Mushishi, as to even call them a form of life would be an oversimplification. Detailed information on Mushi is scarce because the majority of humans are unaware of their existence. So what are Mushi and why do they exist? This is the question that a "Mushishi," Ginko, ponders constantly. Mushishi are those who research Mushi in hopes of understanding their place in the world's hierarchy of life. Ginko chases rumors of occurrences that could be tied to Mushi, all for the sake of finding an answer. It could, after all, lead to the meaning of life itself. [Written by MAL Rewrite]

Within the domed city of Romdo lies one of the last human civilizations on Earth. Thousands of years ago, a global ecological catastrophe doomed the planet; now, life outside these domes is virtually impossible. To expedite mankind's recovery, "AutoReivs," humanoid-like robots, have been created to assist people in their day-to-day lives. However, AutoReivs have begun contracting an enigmatic disease called the "Cogito Virus" which grants them self-awareness. Re-l Mayer, granddaughter of Romdo's ruler, is assigned to investigate this phenomenon alongside her AutoReiv partner Iggy. But what begins as a routine investigation quickly spirals into a conspiracy as Re-l is confronted by humanity's darkest sins. Elsewhere in Romdo, an AutoReiv specialist by the name of Vincent Law must also face his demons when surreal events begin occurring around him. Re-l, Iggy, Vincent, and the child AutoReiv named Pino, will form an unlikely faction as they struggle to uncover Romdo's mysteries and ultimately, discover the true purpose of the mythical beings called "Proxies." [Written by MAL Rewrite]

Dr. Kenzou Tenma, an elite neurosurgeon recently engaged to his hospital director's daughter, is well on his way to ascending the hospital hierarchy. That is until one night, a seemingly small event changes Dr. Tenma's life forever. While preparing to perform surgery on someone, he gets a call from the hospital director telling him to switch patients and instead perform life-saving brain surgery on a famous performer. His fellow doctors, fiancée, and the hospital director applaud his accomplishment; but because of the switch, a poor immigrant worker is dead, causing Dr. Tenma to have a crisis of conscience. So when a similar situation arises, Dr. Tenma stands his ground and chooses to perform surgery on the young boy Johan Liebert instead of the town's mayor. Unfortunately, this choice leads to serious ramifications for Dr. Tenma—losing his social standing being one of them. However, with the mysterious death of the director and two other doctors, Dr. Tenma's position is restored. With no evidence to convict him, he is released and goes on to attain the position of hospital director. Nine years later when Dr. Tenma saves the life of a criminal, his past comes back to haunt him—once again, he comes face to face with the monster he operated on. He must now embark on a quest of pursuit to make amends for the havoc spread by the one he saved. [Written by MAL Rewrite]

Kyon, your typical high school student, has long given up his belief in the supernatural. However, upon meeting Haruhi Suzumiya, he quickly finds out that it is the supernatural that she is interested in—aliens, time travelers, and espers among other things. When Haruhi laments about the lack of intriguing clubs around school, Kyon inspires Haruhi to form her own club. As a result, the SOS Brigade is formed, a club which specializes in all that is the supernatural. Much to his chagrin, Kyon, along with the silent bookworm, Yuki Nagato, the shy and timid Mikuru Asahina, and the perpetually smiling Itsuki Koizumi, are recruited as members. The story follows the crazy adventures that these four endure under their whimsical leader, Haruhi. The story is based on the light novels by Nagaru Tanigawa. [Written by MAL Rewrite]