With dead and lifeless eyes, Rachel Gardner wishes only to die. Waking up in the basement of a building, she has no idea how or why she's there. She stumbles across a bandaged murderer named Zack, who is trying to escape. After promising to kill her as soon as he is free, Rachel and Zack set out to ascend through the building floor by floor until they escape. However, as they progress upward, they meet more twisted people, and all of them seem familiar with Rachel. What is her connection to the building, and why was she placed in it? Facing a new boss on each floor, can Rachel and Zack both achieve their wishes? [Written by MAL Rewrite]

Japan, 1988. An explosion caused by a young boy with psychic powers tears through the city of Tokyo and ignites the fuse that leads to World War III. In order to prevent any further destruction, he is captured and taken into custody, never to be heard from again. Now, in the year 2019, a restored version of the city known as Neo-Tokyo—an area rife with gang violence and terrorism against the current government—stands in its place. Here, Shoutarou Kaneda leads "the Capsules," a group of misfits known for riding large, custom motorcycles and being in constant conflict with their rivals "the Clowns." During one of these battles, Shoutarou's best friend Tetsuo Shima is caught up in an accident with an esper who finds himself in the streets of Tokyo after escaping confinement from a government institution. Through this encounter, Tetsuo begins to develop his own mysterious abilities, as the government seeks to quarantine this latest psychic in a desperate attempt to prevent him from unleashing the destructive power that could once again bring the city to its knees. [Written by MAL Rewrite]

Lucy is a special breed of human referred to as "Diclonius," born with a short pair of horns and invisible telekinetic hands that lands her as a victim of inhumane scientific experimentation by the government. However, once circumstances present her an opportunity to escape, Lucy, corrupted by the confinement and torture, unleashes a torrent of bloodshed as she escapes her captors. During her breakout, she receives a crippling head injury that leaves her with a split personality: someone with the mentality of a harmless child possessing limited speech capacity. In this state of instability, she stumbles upon two college students, Kouta and his cousin Yuka, who unknowingly take an injured fugitive into their care, unaware of her murderous tendencies. This act of kindness will change their lives, as they soon find themselves dragged into the shadowy world of government secrecy and conspiracy. [Written by MAL Rewrite]

Hole—a dark, decrepit, and disorderly district where the strong prey on the weak and death is an ordinary occurrence—is all but befitting of the name given to it. A realm separated from law and ethics, it is a testing ground to the magic users who dominate it. As a race occupying the highest rungs of their society, the magic users think of the denizens of Hole as no more than insects. Murdered, mutilated, and made experiments without a second thought, the powerless Hole dwellers litter the halls of Hole's hospital on a daily basis. Possessing free access to and from the cesspool, and with little challenge to their authority, the magic users appear indomitable to most—aside for a few. Kaiman, more reptile than man, is one such individual. He hunts them on a heedless quest for answers with only a trusted pair of bayonets and his immunity to magic. Cursed by his appearance and tormented by nightmares, magic users are his only clue to restoring his life to normal. With his biggest obstacle being his stomach, his female companion Nikaidou, who runs the restaurant Hungry Bug, is his greatest ally. Set in a gritty world of hellish design, Dorohedoro manages a healthy blend of comedy and lightheartedness with death and carnage. Taking plenty of twists and turns while following the lives of Hole's residents, it weaves a unique world of unearthly origin and dreary appearance not for the squeamish or easily disturbed. [Written by MAL Rewrite]