Devilman features Akira Fudo, a shy and timid teenager who has gone mountain climbing in the Himalayas with his father. While in the middle of the expedition, both father and son are killed in a tragic accident. Akira's body is found and possessed by the demon soldier Devilman, who uses his new human form as a disguise in order to fulfill his mission of causing chaos on Earth in order to pave the way for a demonic invasion of the planet. Before his mission can begin in earnest, Devilman meets Akira's childhood friend Miki Makimura and quickly falls in love with her. Devilman resolves to protect Miki and humanity as a whole by battling against his fellow demons. Demon Tribe leader Zennon becomes greatly angered at Devilman's betrayal and is quick to send Devilman's former comrades to destroy him. The other demons soon learn that Miki is precious to Devilman and he must now work to protect her, as well as protect himself. Will the power of love be able to overcome that of true evil?

Devils cannot take form without a living host. However, if the will of an individual is strong enough, they can overcome the demon and make its power their own, becoming a Devilman. Weak and unassuming, Akira Fudou has always had a bleeding heart. So when his childhood friend Ryou Asuka asks for his help in uncovering devils, Akira accepts without hesitation. However, to Akira's surprise, the place they go to is Sabbath: an immoral party of debauchery and degeneracy. Amidst bloodshed and death, demons possess the partiers, turning their bodies into grotesque monsters, and begin wreaking havoc. In a reckless attempt to save his best friend, Akira unwittingly merges with the devil Amon and becomes a Devilman, gaining the power to defeat the remaining demons. Though it grants him great power, this new partnership awakens an insatiable and primeval part of Akira. Having the body of a devil but the same crybaby heart, Akira works alongside Ryou, destroying those that harm humanity and his loved ones. [Written by MAL Rewrite]

Fear runs rampant throughout Tokyo with the revelation that demons in fact exist amongst us. Paranoia and the darker side of humanity boils onto the streets as people turn on one another, suspecting that anyone could in fact be a demon hiding in human clothing. Amidst the growing tensions, tragedy strikes Akira causing his mind to snap, retreating into his subconscious, allowing his Devilish alter-ego Amon to break free from Akira's cage of flesh and wreak havoc on both human and demons alike.

The heroes of the series Mazinger Z and Devilman fighting against the evil Demon Clan.